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New stem cell centre opens

 

McEwen Centre for Regenerative Medicine

If you watched the news this week and saw singer Bob Geldof walking around science labs and looking through microscopes with the expression, “Which cell are we looking at??”, then you know about the opening of the McEwen Centre for Regenerative Medicine this past Wednesday. Even though Sir Geldof didn’t bless us with a performance, I attended the lectures and met some of the scientists, so I can give you some highlights of the scientific research taking place at the McEwen Centre:

  1. Cure for blindness underway: Researchers from UT have implanted human retinal stem cells into mouse retina and found successful integration, photoreceptor proliferation, and increased low light visual acuity in the mice.
  2. Acute myeloid leukemia can be somewhat controlled by interfering with the migration and adhesion properties of the cancerous stem cells.
  3. Clinical trials have begun for new spinal cord injury therapies using inhibitors and biomaterial guidance channels.
  4. Bone marrow cells can differentiate into lung epithelia in vivo suggesting future studies to regenerate lung, trachea, and even alveoli.

One of the most interesting comments came from the featured speaker of the day, Dr. George Daley, MD, PhD, Harvard MIT. In his overview and history of global stem cell research, he noted Toronto as a stronghold of stem cell research with world class pioneering work. He went on to vindicate and validate the work of South Korean researcher, Dr. Hwang, a once renowned pioneer in stem cell research who fell from grace after a much publicized scandal of falsified research. Dr. Daley’s group thoroughly analyzed Dr. Hwang’s work and found that the dishonoured scientist may have indeed found the first Parthenogenesis embryonic stem cell.

With their motto “Collaborate. Create. Cure.” and events like the one on Wednesday, it seems the McEwen Centre will further solidify Canada’s global position in stem cell research.

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  • http://blog.marsdd.com/ webgoddesscathy @ MaRS

    Richard Branson, the Virgin guru, has thrown his hat in the stem cell ring as well:

    Branson goes from cellphones to stem cells

    How far away is Canada from a “bank” like this?

  • http://blog.marsdd.com/2007/08/17/scandal-ends-redeemed-scientist-gets-credit-for-historic-virgin-birth/ MaRS Blog – Innovation and Commercialization in Canada » Blog Archive » Scandal Ends: Redeemed scientist gets credit for historic “virgin birth”

    [...] But in the last year there have been whispers, reported here last fall, that his work was reanalyzed by multiple top tier labs and found to be legitimate. And now it’s official. Published in last week’s Cell Stem Cell, a team led by Harvard’s Dr. George Daley and including teams from Canada, England, and Japan, reported the official results of their whole-genome analysis of the DNA of Hwang’s stem cells. They verified that Hwang indeed made the historic discovery… the first human cloned cells created by parthogenesis, otherwise, known as “virgin birth.” A very difficult process to master and unlike the usual method of somatic cell nuclear transfer (SCNT), parthogenesis doesn’t require the union of egg and sperm but is initiated spontaneously from the egg alone. The international team analyzed tens of thousands of gene snippets on the cells’ genomes and compared these signatures to those of the egg donor and of the skin cell donor. [...]

Lincoln Kim @ MaRS

Lincoln Kim @ MaRS

Lincoln Kim is a member of the healthcare and life sciences team of the MaRS Venture Group. He evaluates and supports the development of technology platforms and commercial market opportunities of start up and emerging companies, facilitates collaboration among research groups and between research scientists and industry.

 
 
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