NoAb BioDiscoveries
SERVICES OFFERED BY NOAB BIODISCOVERIES
Pharmacokinetic Services for Lead Generation and OptimizationNoAb BioDiscoveries can help you prioritize your hits into leads through pharmacokinetics and metabolism studies. This will assist you in selecting the most promising candidates for future success.
In Vitro Assays
- Cell permeability assays
- Plasma protein binding
- Metabolic stability in hepatocytes
- Metabolic stability in liver subcellular fractions
- Cytochrome P450 enzyme subtype inhibition studies
- Plasma stability assays
- Cytotoxicity assays
- In Vivo Assays
- Pharmacokinetic determinations in rats and mice
- Microdialysis
- Serial collections of cerebrospinal fluid
Other customized assays may be available on request.
LOCATION
2820 Argentia Rd., Unit 8Misissauga, Ont.
L5N 8G4
CONTACT
David K.H. LeeChief Scientific Officer
Phone: 905-814-5238
Toll-free: 1-866-729-6622
E-mail: dkhlee@noabbiodiscoveries.com
Website: www.noabbiodiscoveries.com
ABOUT NoAb BioDISCOVERIES
NoAb BioDiscoveries provides a broad suite of drug discovery services and products to pharmaceutical and biotechnology clients, and develops novel tools for accelerating the drug discovery process. Their scientific team has a proven track record with many years of drug discovery experience. Housed in a new custom-designed 12,600 square-foot facility, NoAb assists its partners with advancing their program through the various phases of lead generation and optimization by using a battery of in vitro ADMET assays followed by in vivo pharmacokinetic studies in mice or rats. Specialized models such as hepatoportal vein and bile duct cannulated rats, microdialysis and serial cerebrospinal fluid collection are also available. In addition, using its own proprietary UniMAC™ activation technology, NoAb provides a wide range of custom-coated microwell plates for HTS.MaRS BLOG
