| 30 October, 1920
|
Frederick Banting conceives an idea for extracting an anti-diabetic pancreatic secretion. |
| 8 November, 1920
|
Banting meets with J.J.R. Macleod, who assigns him a lab and Charles Best as a research assistant. |
| May 1921
|
Banting and Best begin laboratory work. |
| December, 1921
|
J.B. Collip, a specialist in tissue extracts, joins the team. |
| 11 January, 1922
|
First human test on Leonard Thomson. Results are promising, but toxic side-effects prevent further testing. |
| 23 January, 1922
|
Thomson tested again with a refined extract. All symptoms of his diabetes ‘miraculously’ disappear. |
| 22 March, 1922
|
Team publishes its findings, prompting a flurry of media and public attention. |
March-May, 1922
|
Collip temporarily loses ability to produce insulin. Insulin Committee (IC) is created to expand the resource base to develop Insulin for mass-production. |
| 30 May, 1922
|
IC licenses U.S.A. production rights to Eli Lilly & Co. |
| November, 1922
|
IC grants development and production rights to Britain’s “Medical Research Council” and Denmark’s “Nordisk Insulinlaboratorium”. |
| Late 1923
|
Mass-production of Insulin begins. |