Biomedical Assay Development Intern
Wednesday, May 1
Student Work Placement Program
This position is offered in part by the MaRS Student Work Placement program (SWP), which connects post-secondary students with work placements in technology and business.
Position Start Date: May 1, 2019
Position End Date: August 30, 2019 (can extend to 8 months)
ChipCare is developing one of the most versatile point-of-care diagnostics platforms in the world, which will enable an unparalleled sample-to-action workflow in the clinic. Our polyvalent analyzer (PAx) utilizes a patented approach to analyte detection that can perform multiple key assay classes including cell surface markers, proteins and nucleic acids. Using small volumes of patient blood or urine samples, health workers in doctors’ offices and remote health locations will be able to rapidly and accurately perform tests to diagnose or monitor a range of infectious and non-communicable diseases. The company is currently focused on the development and launch of multiplex molecular and immunoassays targeting the Women’s health and STI markets.
Department: Systems integration
This project entails working with the Science and Engineering teams to participate in the development and characterization of multiplex immunoassays and molecular diagnostic assays on ChipCare’s fluidic cartridges
Working as part of Science team you will:
- Assist with activities related to porting bench assays onto fluidic cartridge modules and subsequent testing and integration.
- Run established protocols and probe performance variations based on physical, chemical, and biological variations under controlled conditions.
- Assist with microsphere-based sensor development targeting nucleic acids and proteins related to infectious diseases.
- Actively participate in data capture and analysis for platform testing and improvement.
- Contribute to benchtop assay characterization and comparison testing of prototypes developed in-house to gold standard instrumentation.
- This position will require hands-on work in a CL2 laboratory
Other tasks may be assigned as required.
Note this position may require periodically working with Class 3B or Class 4 lasers and as such will require participation in ChipCare’s Laser radiation medical surveillance program including a pre-assignment baseline optometric examination (administered by a qualified third party). The position may also require working in ChipCare’s biological containment level 2 facility from time to time, under supervision.
ChipCare has a small, highly skilled, collaborative and energized team of ~25 engineers, technologists and scientists working together in a complex co-development project. You will be; working in a fast-paced product development environment, managing relevant project sub tasks within overall project (including task planning, scheduling and reporting), getting hands-on experience in prototype design, build and characterization. Through this project you will build knowledge and experience related to integration of hardware and biochemical assays, develop excellent teamwork and communication skills and contribute to the development of a new platform.
- experience working with analytical instruments, (eg. microscopy, Luminex platforms)
- demonstrated meticulous laboratory bench work
- understanding of the working principles of immunoassays or molecular diagnostic assays
- hands on experience in PCR or ELISA is an asset
- working knowledge of and experience in fluorescence microscopy
- experience with flowcytometry is an asset
- excellent written and verbal communication skills, including laboratory and experimental record keeping, experience in a GLP environment is an asset
- able to develop and execute experimental/analytical test plans, familiarity with design of experiments methodologies is an asset
- excellent organizational and time management skills, ability to work independently with minimal supervision
- ability to work in teams and demonstrate flexibility in task assignments etc in order to ensure project success
- demonstrated familiarity with Laboratory health and safety practices
Area and Level of Study:
Partial undergraduate degree in Biology, Chemistry, Biomedical Engineering (or a related field)